BDBM50027357 1-(4-Carboxy-2-methyl-butyryl)-pyrrolidine-2-carboxylic acid::CHEMBL78780

SMILES: C[C@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(O)=O

InChI Key: InChIKey=VCEONNJJOZVVIA-SFYZADRCSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50027357 (1-(4-Carboxy-2-methyl-butyryl)-pyrrolidine-2-carbo...) Show SMILES C[C@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C11H17NO5/c1-7(4-5-9(13)14)10(15)12-6-2-3-8(12)11(16)17/h7-8H,2-6H2,1H3,(H,13,14)(H,16,17)/t7-,8+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antihypertensive activity against human renin				J Med Chem 24: 355-61 (1981) BindingDB Entry DOI: 10.7270/Q2PC32XP
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027357 (1-(4-Carboxy-2-methyl-butyryl)-pyrrolidine-2-carbo...) Show SMILES C[C@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C11H17NO5/c1-7(4-5-9(13)14)10(15)12-6-2-3-8(12)11(16)17/h7-8H,2-6H2,1H3,(H,13,14)(H,16,17)/t7-,8+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Inhibitory activity against angiotensin converting enzyme (ACE)				J Med Chem 36: 2390-403 (1993) BindingDB Entry DOI: 10.7270/Q2Z320V9
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM50027357 (1-(4-Carboxy-2-methyl-butyryl)-pyrrolidine-2-carbo...) Show SMILES C[C@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(O)=O Show InChI InChI=1S/C11H17NO5/c1-7(4-5-9(13)14)10(15)12-6-2-3-8(12)11(16)17/h7-8H,2-6H2,1H3,(H,13,14)(H,16,17)/t7-,8+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Angiotensin I converting enzyme (ACE) in Bothrops jararaca venom				J Med Chem 45: 5609-16 (2002) BindingDB Entry DOI: 10.7270/Q270825W
					More data for this Ligand-Target Pair