BDBM50027817 CHEMBL345304

SMILES: C[C@H](CNc1ccc(CNC(C)=O)cc1)NC[C@H](O)c1cccc(Cl)c1

InChI Key: InChIKey=PHCQHHUHBQVLPB-VLIAUNLRSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50027817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50027817 (CHEMBL345304) Show SMILES C[C@H](CNc1ccc(CNC(C)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H26ClN3O2/c1-14(22-13-20(26)17-4-3-5-18(21)10-17)11-24-19-8-6-16(7-9-19)12-23-15(2)25/h3-10,14,20,22,24,26H,11-13H2,1-2H3,(H,23,25)/t14-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to cause cAMP accumulation in CHO cells expressing human beta-2 AR expressed as the negative logarithm of the molar drug concentration				J Med Chem 45: 567-83 (2002) BindingDB Entry DOI: 10.7270/Q2W0976P
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50027817 (CHEMBL345304) Show SMILES C[C@H](CNc1ccc(CNC(C)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H26ClN3O2/c1-14(22-13-20(26)17-4-3-5-18(21)10-17)11-24-19-8-6-16(7-9-19)12-23-15(2)25/h3-10,14,20,22,24,26H,11-13H2,1-2H3,(H,23,25)/t14-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to cause cAMP accumulation in CHO cells expressing human beta-1 AR expressed as the negative logarithm of the molar drug concentration				J Med Chem 45: 567-83 (2002) BindingDB Entry DOI: 10.7270/Q2W0976P
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50027817 (CHEMBL345304) Show SMILES C[C@H](CNc1ccc(CNC(C)=O)cc1)NC[C@H](O)c1cccc(Cl)c1 Show InChI InChI=1S/C20H26ClN3O2/c1-14(22-13-20(26)17-4-3-5-18(21)10-17)11-24-19-8-6-16(7-9-19)12-23-15(2)25/h3-10,14,20,22,24,26H,11-13H2,1-2H3,(H,23,25)/t14-,20+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Ability to cause cAMP accumulation in CHO cells expressing human beta-3 AR expressed as the negative logarithm of the molar drug concentration				J Med Chem 45: 567-83 (2002) BindingDB Entry DOI: 10.7270/Q2W0976P
					More data for this Ligand-Target Pair