BDBM50028417 CHEMBL3355134

SMILES: C[C@H]1CN(C)CC[C@H]1c1cc2N3[C@H](C)C(=O)NN=C3COc2cc1-c1c(F)cccc1F

InChI Key: InChIKey=ZGUHOEPQNPFVGZ-RRFJBIMHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50028417 (CHEMBL3355134) Show SMILES C[C@H]1CN(C)CC[C@H]1c1cc2N3[C@H](C)C(=O)NN=C3COc2cc1-c1c(F)cccc1F |r,wU:1.0,12.13,7.8,c:18,(44.88,-28.71,;43.52,-27.99,;42.21,-28.8,;40.85,-28.09,;39.55,-28.9,;40.8,-26.55,;42.1,-25.73,;43.46,-26.45,;44.91,-25.87,;46.24,-26.64,;47.57,-25.87,;48.91,-26.64,;48.91,-28.17,;47.57,-28.95,;50.24,-28.95,;50.24,-30.49,;51.57,-28.17,;51.57,-26.64,;50.24,-25.87,;50.24,-24.33,;48.91,-23.56,;47.57,-24.33,;46.24,-23.56,;44.91,-24.33,;43.55,-23.55,;43.82,-22.03,;45.26,-21.5,;42.64,-21.04,;41.19,-21.57,;40.93,-23.08,;42.11,-24.07,;41.58,-25.52,)| Show InChI InChI=1S/C24H26F2N4O2/c1-13-11-29(3)8-7-15(13)16-9-20-21(10-17(16)23-18(25)5-4-6-19(23)26)32-12-22-27-28-24(31)14(2)30(20)22/h4-6,9-10,13-15H,7-8,11-12H2,1-3H3,(H,28,31)/t13-,14+,15+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...				J Med Chem 58: 333-46 (2015) Article DOI: 10.1021/jm5013006 BindingDB Entry DOI: 10.7270/Q2B859P2
					More data for this Ligand-Target Pair