BDBM50028455 CHEMBL3335645

SMILES: CC(=O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc(cc2)C(C)(C)C)c1

InChI Key: InChIKey=GPQYZRHYWVYERQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50028455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bile acid receptor (Homo sapiens (Human))	BDBM50028455 (CHEMBL3335645) Show SMILES CC(=O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc(cc2)C(C)(C)C)c1 Show InChI InChI=1S/C26H26N2O3/c1-17(29)19-8-7-9-21(16-19)27-25(31)22-10-5-6-11-23(22)28-24(30)18-12-14-20(15-13-18)26(2,3)4/h5-16H,1-4H3,(H,27,31)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Agonist activity at human FXR expressed in human HeLa cells assessed as receptor activation by BSEP promoter-driven firefly luciferase reporter gene ...				J Med Chem 57: 8035-55 (2014) Article DOI: 10.1021/jm500937v BindingDB Entry DOI: 10.7270/Q26H4K06
					More data for this Ligand-Target Pair