BDBM50029100 2-(4-Chloro-phenyl)-1-methyl-ethylamine::CHEMBL358967::para-chloroamphetamine

SMILES: CC(N)Cc1ccc(Cl)cc1

InChI Key: InChIKey=WWPITPSIWMXDPE-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50029100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Invitro inhibitory potency of the compound was measured against phenylethanolamine N-methyltransferase				J Med Chem 23: 506-11 (1980) BindingDB Entry DOI: 10.7270/Q2F47N5S
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of SERT-mediated 5-HT uptake in Wistar rat brain synaptosomes				J Med Chem 21: 978-81 (1979) BindingDB Entry DOI: 10.7270/Q2K9392R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	424	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Inhibition of human dopamine transporter				Eur J Med Chem 44: 4862-88 (2009) Article DOI: 10.1016/j.ejmech.2009.07.027 BindingDB Entry DOI: 10.7270/Q24J0F7W
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at SERT in rat brain synaptosome				Eur J Med Chem 44: 4862-88 (2009) Article DOI: 10.1016/j.ejmech.2009.07.027 BindingDB Entry DOI: 10.7270/Q24J0F7W
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
Trinity College Curated by ChEMBL					Assay Description Inhibition of human noradrenaline transporter				Eur J Med Chem 44: 4862-88 (2009) Article DOI: 10.1016/j.ejmech.2009.07.027 BindingDB Entry DOI: 10.7270/Q24J0F7W
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50029100 (2-(4-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL35...) Show SMILES CC(N)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C9H12ClN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Chile Curated by ChEMBL					Assay Description Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspension				J Med Chem 48: 2407-19 (2005) Article DOI: 10.1021/jm0493109 BindingDB Entry DOI: 10.7270/Q27080XX
					More data for this Ligand-Target Pair