BDBM50029392 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2-dimethyl-piperazine::CHEMBL344216

SMILES: CC1CN(CCN1C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1

InChI Key: InChIKey=NDIIKLHONTYYRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50029392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50029392 (4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2-di...) Show SMILES CC1CN(CCN1C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C21H24ClFN2/c1-14-13-25(10-9-24(14)2)21-12-19(15-3-6-17(23)7-4-15)18-8-5-16(22)11-20(18)21/h3-8,11,14,19,21H,9-10,12-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity against dopamine receptor D2				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029392 (4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2-di...) Show SMILES CC1CN(CCN1C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C21H24ClFN2/c1-14-13-25(10-9-24(14)2)21-12-19(15-3-6-17(23)7-4-15)18-8-5-16(22)11-20(18)21/h3-8,11,14,19,21H,9-10,12-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair