null

SMILES: NC(=O)c1cncc(Oc2ccc3ccccc3c2)c1

InChI Key: InChIKey=QMCVYXOQOQCULB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50030169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human))	BDBM50030169 (CHEMBL3343525) Show SMILES NC(=O)c1cncc(Oc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C16H12N2O2/c17-16(19)13-8-15(10-18-9-13)20-14-6-5-11-3-1-2-4-12(11)7-14/h1-10H,(H2,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of catalytically active human SIRT3 (102 to 399 amino acids) expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-me...				J Med Chem 57: 8340-57 (2014) Article DOI: 10.1021/jm500777s BindingDB Entry DOI: 10.7270/Q2KK9DDH
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50030169 (CHEMBL3343525) Show SMILES NC(=O)c1cncc(Oc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C16H12N2O2/c17-16(19)13-8-15(10-18-9-13)20-14-6-5-11-3-1-2-4-12(11)7-14/h1-10H,(H2,17,19)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of full length human SIRT1 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...				J Med Chem 57: 8340-57 (2014) Article DOI: 10.1021/jm500777s BindingDB Entry DOI: 10.7270/Q2KK9DDH
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50030169 (CHEMBL3343525) Show SMILES NC(=O)c1cncc(Oc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C16H12N2O2/c17-16(19)13-8-15(10-18-9-13)20-14-6-5-11-3-1-2-4-12(11)7-14/h1-10H,(H2,17,19)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of full length human SIRT2 expressed in Escherichia coli BL21 (DE3) cells using fluorogenic 7-amino-4-methylcoumarin (AMC)-labeled peptide...				J Med Chem 57: 8340-57 (2014) Article DOI: 10.1021/jm500777s BindingDB Entry DOI: 10.7270/Q2KK9DDH
					More data for this Ligand-Target Pair