Found 11 hits for monomerid = 50030279 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric Oxide Synthase, endothelial
(Bos taurus (bovine)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Compound was tested for binding affinity against Endothelial nitric oxide synthase |
J Med Chem 40: 3869-70 (1998)
Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT |
More data for this Ligand-Target Pair | |
Nitric-oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid PDB UniChem
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Similars
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Compound was tested for binding affinity against neuronal nitric oxide synthase(nNOS) |
J Med Chem 40: 3869-70 (1998)
Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT |
More data for this Ligand-Target Pair | |
Nitric Oxide Synthase, inducible
(Mus musculus (mouse)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Compound was tested for binding affinity against recombinant inducible nitric oxide synthase (iNOS) from mouse |
J Med Chem 40: 3869-70 (1998)
Article DOI: 10.1021/jm970550g BindingDB Entry DOI: 10.7270/Q2C829ZT |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R& D Charnwood
Curated by ChEMBL
| Assay Description Inhibitory activity against human neuronal nitiric oxide synthase |
J Med Chem 46: 913-6 (2003)
Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Rattus norvegicus) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Tested for inhibition of rat brain inducible nitric oxide synthase |
J Med Chem 37: 3886-8 (1994)
BindingDB Entry DOI: 10.7270/Q29P328V |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R& D Charnwood
Curated by ChEMBL
| Assay Description Inhibitory activity against human endothelial nitiric oxide synthase |
J Med Chem 46: 913-6 (2003)
Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R& D Charnwood
Curated by ChEMBL
| Assay Description Inhibitory activity of compound against human inducible nitiric oxide synthase |
J Med Chem 46: 913-6 (2003)
Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering AG
Curated by ChEMBL
| Assay Description Concentration required to inhibit neuronal nitric oxide synthase |
Bioorg Med Chem Lett 12: 2561-4 (2002)
BindingDB Entry DOI: 10.7270/Q2VD6XS8 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering AG
Curated by ChEMBL
| Assay Description In vitro inhibition of inducible nitric oxide synthase. |
Bioorg Med Chem Lett 12: 2561-4 (2002)
BindingDB Entry DOI: 10.7270/Q2VD6XS8 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering AG
Curated by ChEMBL
| Assay Description In vitro inhibition of endothelial nitric oxide synthase. |
Bioorg Med Chem Lett 12: 2561-4 (2002)
BindingDB Entry DOI: 10.7270/Q2VD6XS8 |
More data for this Ligand-Target Pair | |
Nitric Oxide Synthase, inducible
(Mus musculus (mouse)) | BDBM50030279
![PNG](/data/jpeg/tenK5003/BindingDB_50030279.png) (2-Amino-5-(N'-methyl-guanidino)-pentanoic acid | C...)Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Tested for inhibition of mouse inducible nitric oxide synthase |
J Med Chem 37: 3886-8 (1994)
BindingDB Entry DOI: 10.7270/Q29P328V |
More data for this Ligand-Target Pair | |