BDBM50030792 CHEMBL3342401
SMILES: Brc1ccc(cc1)-c1csc2ncc(CNC(=O)Nc3ccc(cc3)C#N)n12
InChI Key: InChIKey=RUPOOQKSFQRRDN-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM50030792 (CHEMBL3342401) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ del Piemonte Orientale Curated by ChEMBL | Assay Description Inhibition of human recombinant IDO1 assessed as reduction in kynurenine production using L-tryptophan incubated for 60 mins by Ehrlich's reagent bas... | Bioorg Med Chem Lett 28: 651-657 (2018) Article DOI: 10.1016/j.bmcl.2018.01.032 BindingDB Entry DOI: 10.7270/Q24T6MZD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase (Homo sapiens (Human)) | BDBM50030792 (CHEMBL3342401) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of human IDO1 assessed as reduction in convertion of N-formylkynurenine to kynurenine incubated for 30 mins | ACS Med Chem Lett 5: 1119-23 (2014) Article DOI: 10.1021/ml500247w BindingDB Entry DOI: 10.7270/Q2GM88W5 | |||||||||||
More data for this Ligand-Target Pair |