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BDBM50030980 1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL)PYRIMIDINE-2,4(1H,3H)-DIONE::5-(3-Benzyloxy-benzyl)-1-(2-hydroxy-ethoxymethyl)-1H-pyrimidine-2,4-dione::CHEMBL277577

SMILES: OCCOCn1cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]c1=O

InChI Key: InChIKey=CSXNPJKDZKLDET-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030980   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uridine phosphorylase 1


(Mus musculus)		BDBM50030980
PNG
(1-((2-HYDROXYETHOXY)METHYL)-5-(3-(BENZYLOXY)BENZYL...)
Show SMILES OCCOCn1cc(Cc2cccc(OCc3ccccc3)c2)c(=O)[nH]c1=O
Show InChI InChI=1S/C21H22N2O5/c24-9-10-27-15-23-13-18(20(25)22-21(23)26)11-17-7-4-8-19(12-17)28-14-16-5-2-1-3-6-16/h1-8,12-13,24H,9-11,14-15H2,(H,22,25,26)
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PubMed
n/an/a 84n/an/an/an/an/an/a



Burroughs Wellcome Co.

Curated by ChEMBL


Assay Description
Inhibition of uridine phosphorylase (UrdPase) from murine liver.

J Med Chem 38: 3850-6 (1995)


BindingDB Entry DOI: 10.7270/Q2B27T91
More data for this
Ligand-Target Pair