BDBM50030994 5-Benzo[1,3]dioxol-5-ylmethyl-1H-pyrimidine-2,4-dione::CHEMBL124537

SMILES: O=c1[nH]cc(Cc2ccc3OCOc3c2)c(=O)[nH]1

InChI Key: InChIKey=XXHWOENZMHTWGE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50030994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine phosphorylase 1 (Mus musculus)	BDBM50030994 (5-Benzo[1,3]dioxol-5-ylmethyl-1H-pyrimidine-2,4-di...) Show SMILES O=c1[nH]cc(Cc2ccc3OCOc3c2)c(=O)[nH]1 Show InChI InChI=1S/C12H10N2O4/c15-11-8(5-13-12(16)14-11)3-7-1-2-9-10(4-7)18-6-17-9/h1-2,4-5H,3,6H2,(H2,13,14,15,16)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burroughs Wellcome Co. Curated by ChEMBL					Assay Description Inhibition of uridine phosphorylase (UrdPase) from murine liver.				J Med Chem 38: 3850-6 (1995) BindingDB Entry DOI: 10.7270/Q2B27T91
					More data for this Ligand-Target Pair