BDBM50031044 3-(3-Bromo-phenyl)-indeno[1,2-c]pyridazin-5-one::3-(3-bromophenyl)-5H-indeno[1,2-c]pyridazin-5-one::CHEMBL127622

SMILES: Brc1cccc(c1)-c1cc2C(=O)c3ccccc3-c2nn1

InChI Key: InChIKey=QJWHHMRBGUTLMX-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031044 (3-(3-Bromo-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES Brc1cccc(c1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9BrN2O/c18-11-5-3-4-10(8-11)15-9-14-16(20-19-15)12-6-1-2-7-13(12)17(14)21/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase B enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031044 (3-(3-Bromo-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES Brc1cccc(c1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9BrN2O/c18-11-5-3-4-10(8-11)15-9-14-16(20-19-15)12-6-1-2-7-13(12)17(14)21/h1-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	661	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50031044 (3-(3-Bromo-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES Brc1cccc(c1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9BrN2O/c18-11-5-3-4-10(8-11)15-9-14-16(20-19-15)12-6-1-2-7-13(12)17(14)21/h1-9H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.62	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of human supersomes MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50031044 (3-(3-Bromo-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES Brc1cccc(c1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9BrN2O/c18-11-5-3-4-10(8-11)15-9-14-16(20-19-15)12-6-1-2-7-13(12)17(14)21/h1-9H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase A enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair