BDBM50031047 3-(4-Nitro-phenyl)-indeno[1,2-c]pyridazin-5-one::3-(4-nitrophenyl)-5H-indeno[1,2-c]pyridazin-5-one::CHEMBL124935

SMILES: [O-][N+](=O)c1ccc(cc1)-c1cc2C(=O)c3ccccc3-c2nn1

InChI Key: InChIKey=GCMBFNZCNIURJG-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50031047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031047 (3-(4-Nitro-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9N3O3/c21-17-13-4-2-1-3-12(13)16-14(17)9-15(18-19-16)10-5-7-11(8-6-10)20(22)23/h1-9H	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
Université de Neuchâtel Curated by ChEMBL					Assay Description Inhibitory activity against Monoamine oxidase B from rat brain mitochondria				J Med Chem 41: 3812-20 (1998) Article DOI: 10.1021/jm981005y BindingDB Entry DOI: 10.7270/Q2F18XVD
					More data for this Ligand-Target Pair
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50031047 (3-(4-Nitro-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9N3O3/c21-17-13-4-2-1-3-12(13)16-14(17)9-15(18-19-16)10-5-7-11(8-6-10)20(22)23/h1-9H	PDB MMDB B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase A enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031047 (3-(4-Nitro-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9N3O3/c21-17-13-4-2-1-3-12(13)16-14(17)9-15(18-19-16)10-5-7-11(8-6-10)20(22)23/h1-9H	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of rat brain MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50031047 (3-(4-Nitro-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9N3O3/c21-17-13-4-2-1-3-12(13)16-14(17)9-15(18-19-16)10-5-7-11(8-6-10)20(22)23/h1-9H	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.32	n/a	n/a	n/a	n/a	n/a	n/a
University of Geneva Curated by ChEMBL					Assay Description Inhibition of human supersomes MAOB				J Med Chem 49: 6264-72 (2006) Article DOI: 10.1021/jm060441e BindingDB Entry DOI: 10.7270/Q2X63P5Q
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031047 (3-(4-Nitro-phenyl)-indeno[1,2-c]pyridazin-5-one | ...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc2C(=O)c3ccccc3-c2nn1 Show InChI InChI=1S/C17H9N3O3/c21-17-13-4-2-1-3-12(13)16-14(17)9-15(18-19-16)10-5-7-11(8-6-10)20(22)23/h1-9H	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase B enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair