BDBM50031056 7-Hydroxy-3-(3-trifluoromethyl-phenyl)-indeno[1,2-c]pyridazin-5-one::CHEMBL339470

SMILES: Oc1ccc-2c(c1)C(=O)c1cc(nnc-21)-c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=HUYIXXMTRXNSBV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50031056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50031056 (7-Hydroxy-3-(3-trifluoromethyl-phenyl)-indeno[1,2-...) Show SMILES Oc1ccc-2c(c1)C(=O)c1cc(nnc-21)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H9F3N2O2/c19-18(20,21)10-3-1-2-9(6-10)15-8-14-16(23-22-15)12-5-4-11(24)7-13(12)17(14)25/h1-8,24H	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase A enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50031056 (7-Hydroxy-3-(3-trifluoromethyl-phenyl)-indeno[1,2-...) Show SMILES Oc1ccc-2c(c1)C(=O)c1cc(nnc-21)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H9F3N2O2/c19-18(20,21)10-3-1-2-9(6-10)15-8-14-16(23-22-15)12-5-4-11(24)7-13(12)17(14)25/h1-8,24H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Lausanne Curated by ChEMBL					Assay Description Ability to inhibit Monoamine oxidase B enzyme				J Med Chem 38: 3874-83 (1995) BindingDB Entry DOI: 10.7270/Q26972M4
					More data for this Ligand-Target Pair