BDBM50031928 6-Piperazin-1-yl-7,8-dihydro-benzo[k]phenanthridine::CHEMBL62636

SMILES: C1CN(CCN1)c1nc2ccccc2c-2c1CCc1ccccc-21

InChI Key: InChIKey=MBYSZSSLCHLOCQ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50031928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50031928 (6-Piperazin-1-yl-7,8-dihydro-benzo[k]phenanthridin...) Show SMILES C1CN(CCN1)c1nc2ccccc2c-2c1CCc1ccccc-21 Show InChI InChI=1S/C21H21N3/c1-2-6-16-15(5-1)9-10-18-20(16)17-7-3-4-8-19(17)23-21(18)24-13-11-22-12-14-24/h1-8,22H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligand				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor (Rattus norvegicus-RAT)	BDBM50031928 (6-Piperazin-1-yl-7,8-dihydro-benzo[k]phenanthridin...) Show SMILES C1CN(CCN1)c1nc2ccccc2c-2c1CCc1ccccc-21 Show InChI InChI=1S/C21H21N3/c1-2-6-16-15(5-1)9-10-18-20(16)17-7-3-4-8-19(17)23-21(18)24-13-11-22-12-14-24/h1-8,22H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonist				J Med Chem 41: 2029-39 (1998) Article DOI: 10.1021/jm970745o BindingDB Entry DOI: 10.7270/Q2CJ8H7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50031928 (6-Piperazin-1-yl-7,8-dihydro-benzo[k]phenanthridin...) Show SMILES C1CN(CCN1)c1nc2ccccc2c-2c1CCc1ccccc-21 Show InChI InChI=1S/C21H21N3/c1-2-6-16-15(5-1)9-10-18-20(16)17-7-3-4-8-19(17)23-21(18)24-13-11-22-12-14-24/h1-8,22H,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50031928 (6-Piperazin-1-yl-7,8-dihydro-benzo[k]phenanthridin...) Show SMILES C1CN(CCN1)c1nc2ccccc2c-2c1CCc1ccccc-21 Show InChI InChI=1S/C21H21N3/c1-2-6-16-15(5-1)9-10-18-20(16)17-7-3-4-8-19(17)23-21(18)24-13-11-22-12-14-24/h1-8,22H,9-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Effect of compound on Serotonin transporter uptake from rat cortex using [3H]citalopram as radioligand				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair