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SMILES: COc1cc2c(nc3ccccc3c2c2ccccc12)N1CCNCC1

InChI Key: InChIKey=RYOMVLBXPZVFIK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50031941   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50031941 (8-Methoxy-6-piperazin-1-yl-benzo[k]phenanthridine ...) Show SMILES COc1cc2c(nc3ccccc3c2c2ccccc12)N1CCNCC1 Show InChI InChI=1S/C22H21N3O/c1-26-20-14-18-21(16-7-3-2-6-15(16)20)17-8-4-5-9-19(17)24-22(18)25-12-10-23-11-13-25/h2-9,14,23H,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Rat 5-hydroxytryptamine 3 receptor (5-HT3) antagonist				J Med Chem 41: 2029-39 (1998) Article DOI: 10.1021/jm970745o BindingDB Entry DOI: 10.7270/Q2CJ8H7X
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50031941 (8-Methoxy-6-piperazin-1-yl-benzo[k]phenanthridine ...) Show SMILES COc1cc2c(nc3ccccc3c2c2ccccc12)N1CCNCC1 Show InChI InChI=1S/C22H21N3O/c1-26-20-14-18-21(16-7-3-2-6-15(16)20)17-8-4-5-9-19(17)24-22(18)25-12-10-23-11-13-25/h2-9,14,23H,10-13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligand				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50031941 (8-Methoxy-6-piperazin-1-yl-benzo[k]phenanthridine ...) Show SMILES COc1cc2c(nc3ccccc3c2c2ccccc12)N1CCNCC1 Show InChI InChI=1S/C22H21N3O/c1-26-20-14-18-21(16-7-3-2-6-15(16)20)17-8-4-5-9-19(17)24-22(18)25-12-10-23-11-13-25/h2-9,14,23H,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 2A receptor from rat cortex assayed using [3H]ketanserin as radioligand.				J Med Chem 38: 2692-704 (1995) BindingDB Entry DOI: 10.7270/Q27H1K7H
					More data for this Ligand-Target Pair