BDBM50032113 2-[2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phenyl-amino)-quinazolin-8-yloxy]-ethanol::CHEMBL96619::TCMDC-142334

SMILES: CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(OCCO)cccc12

InChI Key: InChIKey=ONYBTOHSSKYVDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50032113 (2-[2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phe...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(OCCO)cccc12 Show InChI InChI=1S/C24H23FN4O2/c1-16-15-17(25)11-12-20(16)26-24-27-22-19(9-6-10-21(22)31-14-13-30)23(28-24)29(2)18-7-4-3-5-8-18/h3-12,15,30H,13-14H2,1-2H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair