BDBM50032126 2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phenyl-amino)-quinazolin-8-ol::CHEMBL432001

SMILES: CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(O)cccc12

InChI Key: InChIKey=DEVJTOGYUBPZFN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50032126 (2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phenyl...) Show SMILES CN(c1ccccc1)c1nc(Nc2ccc(F)cc2C)nc2c(O)cccc12 Show InChI InChI=1S/C22H19FN4O/c1-14-13-15(23)11-12-18(14)24-22-25-20-17(9-6-10-19(20)28)21(26-22)27(2)16-7-4-3-5-8-16/h3-13,28H,1-2H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair