BDBM50032141 CHEMBL92888::[2-(4-Fluoro-2-methyl-phenylamino)-4-(methyl-phenyl-amino)-quinazolin-8-yloxy]-acetic acid ethyl ester

SMILES: CCOC(=O)COc1cccc2c(nc(Nc3ccc(F)cc3C)nc12)N(C)c1ccccc1

InChI Key: InChIKey=TXWUNNAZIKLWPG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50032141 (CHEMBL92888 | [2-(4-Fluoro-2-methyl-phenylamino)-4...) Show SMILES CCOC(=O)COc1cccc2c(nc(Nc3ccc(F)cc3C)nc12)N(C)c1ccccc1 Show InChI InChI=1S/C26H25FN4O3/c1-4-33-23(32)16-34-22-12-8-11-20-24(22)29-26(28-21-14-13-18(27)15-17(21)2)30-25(20)31(3)19-9-6-5-7-10-19/h5-15H,4,16H2,1-3H3,(H,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair