BDBM50032146 6-(3-Dimethylamino-propoxy)-N*2*-(4-fluoro-2-methyl-phenyl)-N*4*-methyl-N*4*-phenyl-quinazoline-2,4-diamine::CHEMBL318271::TCMDC-142332

SMILES: CN(C)CCCOc1ccc2nc(Nc3ccc(F)cc3C)nc(N(C)c3ccccc3)c2c1

InChI Key: InChIKey=FKLRFZZNODMAAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50032146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50032146 (6-(3-Dimethylamino-propoxy)-N*2*-(4-fluoro-2-methy...) Show SMILES CN(C)CCCOc1ccc2nc(Nc3ccc(F)cc3C)nc(N(C)c3ccccc3)c2c1 Show InChI InChI=1S/C27H30FN5O/c1-19-17-20(28)11-13-24(19)29-27-30-25-14-12-22(34-16-8-15-32(2)3)18-23(25)26(31-27)33(4)21-9-6-5-7-10-21/h5-7,9-14,17-18H,8,15-16H2,1-4H3,(H,29,30,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R & D Curated by ChEMBL					Assay Description Inhibition of K+ stimulated gastric ATPase activity				J Med Chem 38: 2763-73 (1995) BindingDB Entry DOI: 10.7270/Q2TT4Q0J
					More data for this Ligand-Target Pair