null
SMILES: C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(cc1)-c1ccsc1
InChI Key: InChIKey=FIDHUVXPTUSGFR-IINYFYTJSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50032457 (CHEMBL3354143 | US9353075, 45) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | 7.4 | n/a |
The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” US Patent | Assay Description Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai... | US Patent US9353075 (2016) BindingDB Entry DOI: 10.7270/Q23N229Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50032457 (CHEMBL3354143 | US9353075, 45) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Italiano di Tecnologia Curated by ChEMBL | Assay Description Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method | J Med Chem 57: 10101-11 (2014) Article DOI: 10.1021/jm501455s BindingDB Entry DOI: 10.7270/Q26111W8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat)) | BDBM50032457 (CHEMBL3354143 | US9353075, 45) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Italiano di Tecnologia Curated by ChEMBL | Assay Description Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method | J Med Chem 57: 10101-11 (2014) Article DOI: 10.1021/jm501455s BindingDB Entry DOI: 10.7270/Q26111W8 | |||||||||||
More data for this Ligand-Target Pair |