BDBM50033104 CHEMBL3357068

SMILES: CN1CCN(C(=O)C1)c1ccc(cc1)-c1ncc2CCN(CCCN3CCOCC3)c2n1

InChI Key: InChIKey=MFMKTDZALVDFAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50033104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 9 (Homo sapiens (Human))	BDBM50033104 (CHEMBL3357068) Show SMILES CN1CCN(C(=O)C1)c1ccc(cc1)-c1ncc2CCN(CCCN3CCOCC3)c2n1 Show InChI InChI=1S/C24H32N6O2/c1-27-11-12-30(22(31)18-27)21-5-3-19(4-6-21)23-25-17-20-7-10-29(24(20)26-23)9-2-8-28-13-15-32-16-14-28/h3-6,17H,2,7-16,18H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Dainippon Pharma Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human TLR9 transfected in HEK293 cells after 6 hrs by NF-kappaB luciferase reporter assay				ACS Med Chem Lett 5: 1235-9 (2014) Article DOI: 10.1021/ml5003184 BindingDB Entry DOI: 10.7270/Q2M32XBN
					More data for this Ligand-Target Pair