BindingDB PrimarySearch

BDBM50034368 CHEMBL28313::Trifluoro-methanesulfonic acid 7-propylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester

SMILES: CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1

InChI Key: InChIKey=ZRWGXXAMGVLDQT-UHFFFAOYSA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50034368
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (5HT1A) (Mus musculus (Mouse))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligand				J Med Chem 38: 1319-29 (1995) BindingDB Entry DOI: 10.7270/Q24F1RD6
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medicinaregatan Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligand				J Med Chem 36: 3409-16 (1993) BindingDB Entry DOI: 10.7270/Q2X067NP
Medicinaregatan Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]5-HT as radioligand				J Med Chem 38: 1319-29 (1995) BindingDB Entry DOI: 10.7270/Q24F1RD6
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding affinity towards Dopamine receptor D2 by using [3H]U-86170 as radioligand				J Med Chem 38: 1319-29 (1995) BindingDB Entry DOI: 10.7270/Q24F1RD6
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	169	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding affinity towards 5-hydroxytryptamine 1D receptor beta by using [3H]5-HT as radioligand				J Med Chem 38: 1319-29 (1995) BindingDB Entry DOI: 10.7270/Q24F1RD6
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>413	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding affinity towards Dopamine receptor D2 by using [3H]spiperone as radioligand				J Med Chem 38: 1319-29 (1995) BindingDB Entry DOI: 10.7270/Q24F1RD6
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	691	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro binding affinity towards Dopamine receptor D3 by using [3H]spiperone as radioligand				J Med Chem 38: 1319-29 (1995) BindingDB Entry DOI: 10.7270/Q24F1RD6
University of G£teborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50034368 (CHEMBL28313 \| Trifluoro-methanesulfonic acid 7-pro...) Show SMILES CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medicinaregatan Curated by ChEMBL					Assay Description Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperone				J Med Chem 36: 3409-16 (1993) BindingDB Entry DOI: 10.7270/Q2X067NP
Medicinaregatan Curated by ChEMBL					More data for this Ligand-Target Pair