BDBM50034778 CHEMBL3360972

SMILES: CC(C)(O)c1cn(c(n1)-c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O

InChI Key: InChIKey=LZUBEQUFSVAVEB-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034778 (CHEMBL3360972) Show SMILES CC(C)(O)c1cn(c(n1)-c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O |(.07,-55.05,;1.6,-55.21,;2.22,-56.62,;.5,-56.3,;2.5,-53.97,;4.04,-53.97,;4.53,-52.5,;3.27,-51.6,;2.03,-52.51,;3.27,-50.06,;1.94,-49.3,;.61,-50.08,;1.93,-47.77,;3.27,-46.98,;4.61,-47.75,;4.61,-49.29,;6.09,-48.88,;5.84,-51.71,;7.18,-52.45,;8.5,-51.66,;8.47,-50.12,;7.12,-49.38,;5.8,-50.17,;9.79,-49.32,;11.14,-50.07,;12.45,-49.27,;12.42,-47.73,;11.06,-46.99,;9.75,-47.79,;11.02,-45.45,;12.34,-44.64,;9.53,-45.04,;10.62,-43.95,)| Show InChI InChI=1S/C25H22Cl2N2O3S/c1-25(2,30)22-15-29(24(28-22)23-20(26)8-5-9-21(23)27)18-12-10-16(11-13-18)17-6-4-7-19(14-17)33(3,31)32/h4-15,30H,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034778 (CHEMBL3360972) Show SMILES CC(C)(O)c1cn(c(n1)-c1c(Cl)cccc1Cl)-c1ccc(cc1)-c1cccc(c1)S(C)(=O)=O |(.07,-55.05,;1.6,-55.21,;2.22,-56.62,;.5,-56.3,;2.5,-53.97,;4.04,-53.97,;4.53,-52.5,;3.27,-51.6,;2.03,-52.51,;3.27,-50.06,;1.94,-49.3,;.61,-50.08,;1.93,-47.77,;3.27,-46.98,;4.61,-47.75,;4.61,-49.29,;6.09,-48.88,;5.84,-51.71,;7.18,-52.45,;8.5,-51.66,;8.47,-50.12,;7.12,-49.38,;5.8,-50.17,;9.79,-49.32,;11.14,-50.07,;12.45,-49.27,;12.42,-47.73,;11.06,-46.99,;9.75,-47.79,;11.02,-45.45,;12.34,-44.64,;9.53,-45.04,;10.62,-43.95,)| Show InChI InChI=1S/C25H22Cl2N2O3S/c1-25(2,30)22-15-29(24(28-22)23-20(26)8-5-9-21(23)27)18-12-10-16(11-13-18)17-6-4-7-19(14-17)33(3,31)32/h4-15,30H,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	670	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair