BDBM50034780 CHEMBL3360970

SMILES: CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-n1cc(nc1-c1ccccc1Cl)C(F)(F)F

InChI Key: InChIKey=IWVRHURFJVBGSF-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50034780   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50034780 (CHEMBL3360970) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-n1cc(nc1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-16(13-18)15-9-11-17(12-10-15)29-14-21(23(25,26)27)28-22(29)19-7-2-3-8-20(19)24/h2-14H,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50034780 (CHEMBL3360970) Show SMILES CS(=O)(=O)c1cccc(c1)-c1ccc(cc1)-n1cc(nc1-c1ccccc1Cl)C(F)(F)F Show InChI InChI=1S/C23H16ClF3N2O2S/c1-32(30,31)18-6-4-5-16(13-18)15-9-11-17(12-10-15)29-14-21(23(25,26)27)28-22(29)19-7-2-3-8-20(19)24/h2-14H,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assay				Bioorg Med Chem Lett 25: 372-7 (2014) Article DOI: 10.1016/j.bmcl.2014.11.029 BindingDB Entry DOI: 10.7270/Q2154JN9
					More data for this Ligand-Target Pair