BDBM50035578 CHEMBL3356621

SMILES: O=C(N(Cc1ccccc1)Cc1ccccc1)c1cnc2ccccc2c1

InChI Key: InChIKey=USUJGIHUBPRKEZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50035578 (CHEMBL3356621) Show SMILES O=C(N(Cc1ccccc1)Cc1ccccc1)c1cnc2ccccc2c1 Show InChI InChI=1S/C24H20N2O/c27-24(22-15-21-13-7-8-14-23(21)25-16-22)26(17-19-9-3-1-4-10-19)18-20-11-5-2-6-12-20/h1-16H,17-18H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assay				J Med Chem 57: 9776-95 (2014) Article DOI: 10.1021/jm5012808 BindingDB Entry DOI: 10.7270/Q2TH8P9K
					More data for this Ligand-Target Pair