BDBM50035600 CHEMBL3356634

SMILES: O=C(Nc1ccc2[nH]ccc2c1)c1c[nH]c2ccccc2c1=O

InChI Key: InChIKey=PIXCZJVPKHUCFR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50035600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM50035600 (CHEMBL3356634) Show SMILES O=C(Nc1ccc2[nH]ccc2c1)c1c[nH]c2ccccc2c1=O Show InChI InChI=1S/C18H13N3O2/c22-17-13-3-1-2-4-16(13)20-10-14(17)18(23)21-12-5-6-15-11(9-12)7-8-19-15/h1-10,19H,(H,20,22)(H,21,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Potentiation of human CFTR F508del mutant expressed in mouse NIH-3T3 cells after 30 mins by fluorescent voltage sensing optical assay				J Med Chem 57: 9776-95 (2014) Article DOI: 10.1021/jm5012808 BindingDB Entry DOI: 10.7270/Q2TH8P9K
					More data for this Ligand-Target Pair