BDBM50036237 CHEMBL350230::N-[4-((2S,6S,11S)-8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2,6-methano-benzo[d]azocin-3-ylmethyl)-phenyl]-acetamide

SMILES: C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(NC(C)=O)cc1

InChI Key: InChIKey=JWXPPVJRCLFJOJ-QABPDZFRSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036237   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50036237 (CHEMBL350230 | N-[4-((2S,6S,11S)-8-Hydroxy-6,11-di...) Show SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2Cc1ccc(NC(C)=O)cc1 |TLB:16:15:1:10.4.3| Show InChI InChI=1S/C23H28N2O2/c1-15-22-12-18-6-9-20(27)13-21(18)23(15,3)10-11-25(22)14-17-4-7-19(8-5-17)24-16(2)26/h4-9,13,15,22,27H,10-12,14H2,1-3H3,(H,24,26)/t15-,22+,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at Sigma receptor type 1, displacement of [3H]-(+)-pentazocine from guinea pig brain membranes				J Med Chem 38: 565-9 (1995) BindingDB Entry DOI: 10.7270/Q2X63M0N
					More data for this Ligand-Target Pair