BDBM50036265 CHEMBL155260::{(1S,2R)-1-Benzyl-2-hydroxy-3-[(3-methyl-butyl)-phenylmethanesulfonyl-amino]-propyl}-carbamic acid benzyl ester
SMILES: CC(C)CCN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)S(=O)(=O)Cc1ccccc1
InChI Key: InChIKey=WBDHSTSWDLNAGV-URLMMPGGSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50036265![]() (CHEMBL155260 | {(1S,2R)-1-Benzyl-2-hydroxy-3-[(3-m...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Discovery Research Curated by ChEMBL | Assay Description Ability of the compound to inhibit HIV-1 protease was determined using spectrofluorometric assay. | J Med Chem 38: 581-4 (1995) BindingDB Entry DOI: 10.7270/Q2SF2V61 | |||||||||||
More data for this Ligand-Target Pair |