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SMILES: C[C@H]1C[C@@H](C)c2c(C1)ccc(C)c2\C=C\C=C\C(O)=O

InChI Key: InChIKey=GCHCATJQYLAKIS-UFSSINQASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036280   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50036280
PNG
(CHEMBL3353035)
Show SMILES C[C@H]1C[C@@H](C)c2c(C1)ccc(C)c2\C=C\C=C\C(O)=O |r|
Show InChI InChI=1S/C18H22O2/c1-12-10-14(3)18-15(11-12)9-8-13(2)16(18)6-4-5-7-17(19)20/h4-9,12,14H,10-11H2,1-3H3,(H,19,20)/b6-4+,7-5+/t12-,14+/m0/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 8.20E+3n/an/an/an/an/an/a



Wonkwang University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PTP1B assessed as reduction in pNPP substrate hydrolysis incubated for 30 mins

Bioorg Med Chem Lett 24: 5787-91 (2014)


Article DOI: 10.1016/j.bmcl.2014.10.035
BindingDB Entry DOI: 10.7270/Q2KS6T4T
More data for this
Ligand-Target Pair