BDBM50036311 CHEMBL3353074
SMILES: COc1cc(cc(OC)c1OC)C(=O)OCCCN1CCCN(CCOC(=O)c2cc(OC)c(OC)c(OC)c2)CC1
InChI Key: InChIKey=KBNCGWVIKQLCHR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human)) | BDBM50036311 (CHEMBL3353074) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of human ENT1 expressed in porcine PK15NTD cells by cell-based [3H]5-uridine uptake assay | Bioorg Med Chem Lett 24: 5801-4 (2014) Article DOI: 10.1016/j.bmcl.2014.10.026 BindingDB Entry DOI: 10.7270/Q26M38FZ | |||||||||||
More data for this Ligand-Target Pair |