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SMILES: CNC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ncc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=NTXUMDYTLHJDCT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036519   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM50036519
PNG
(CHEMBL3353575)
Show SMILES CNC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ncc(cc1Cl)C(F)(F)F
Show InChI InChI=1S/C21H17ClF3N3O3S/c1-26-20(29)15-7-9-17(10-8-15)32(30,31)28(13-14-5-3-2-4-6-14)19-18(22)11-16(12-27-19)21(23,24)25/h2-12H,13H2,1H3,(H,26,29)
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Article
PubMed
n/an/a 57n/an/an/an/an/an/a



RaQualia Pharma Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx

Bioorg Med Chem Lett 24: 5364-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.10.074
BindingDB Entry DOI: 10.7270/Q2TB18HX
More data for this
Ligand-Target Pair