BDBM50036559 CHEMBL3353584

SMILES: Cc1cc(cnc1N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)C(O)=O)C(F)(F)F

InChI Key: InChIKey=QSHZUPQNJLCBOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM50036559 (CHEMBL3353584) Show SMILES Cc1cc(cnc1N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)C(O)=O)C(F)(F)F Show InChI InChI=1S/C21H17F3N2O4S/c1-14-11-17(21(22,23)24)12-25-19(14)26(13-15-5-3-2-4-6-15)31(29,30)18-9-7-16(8-10-18)20(27)28/h2-12H,13H2,1H3,(H,27,28)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	736	n/a	n/a	n/a	n/a	n/a	n/a
RaQualia Pharma Inc. Curated by ChEMBL					Assay Description Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx				Bioorg Med Chem Lett 24: 5364-8 (2014) Article DOI: 10.1016/j.bmcl.2014.10.074 BindingDB Entry DOI: 10.7270/Q2TB18HX
					More data for this Ligand-Target Pair