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SMILES: OCCNC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ncc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=TUAVQGYGMJCFLF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036567   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM50036567
PNG
(CHEMBL3353577)
Show SMILES OCCNC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1ncc(cc1Cl)C(F)(F)F
Show InChI InChI=1S/C22H19ClF3N3O4S/c23-19-12-17(22(24,25)26)13-28-20(19)29(14-15-4-2-1-3-5-15)34(32,33)18-8-6-16(7-9-18)21(31)27-10-11-30/h1-9,12-13,30H,10-11,14H2,(H,27,31)
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PubMed
n/an/a 216n/an/an/an/an/an/a



RaQualia Pharma Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPM8 expressed in HEK293 cells assessed as inhibition of menthol induced Ca2+ influx

Bioorg Med Chem Lett 24: 5364-8 (2014)


Article DOI: 10.1016/j.bmcl.2014.10.074
BindingDB Entry DOI: 10.7270/Q2TB18HX
More data for this
Ligand-Target Pair