BDBM50037293 CHEMBL3356306

SMILES: OCC1CCN(CC1)c1nccnc1OC1CN(C1)c1nc2ccccc2s1

InChI Key: InChIKey=ZLTVSWBCHPHOOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50037293 (CHEMBL3356306) Show SMILES OCC1CCN(CC1)c1nccnc1OC1CN(C1)c1nc2ccccc2s1 Show InChI InChI=1S/C20H23N5O2S/c26-13-14-5-9-24(10-6-14)18-19(22-8-7-21-18)27-15-11-25(12-15)20-23-16-3-1-2-4-17(16)28-20/h1-4,7-8,14-15,26H,5-6,9-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assay				Bioorg Med Chem 22: 6570-85 (2015) Article DOI: 10.1016/j.bmc.2014.10.013 BindingDB Entry DOI: 10.7270/Q2RB766Q
					More data for this Ligand-Target Pair