BDBM50037294 CHEMBL3356650

SMILES: OCC1CCN(CC1)c1cccnc1OC1CN(C1)c1ccc2ccccc2n1

InChI Key: InChIKey=WGNXRQXVNKMWRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50037294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50037294 (CHEMBL3356650) Show SMILES OCC1CCN(CC1)c1cccnc1OC1CN(C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C23H26N4O2/c28-16-17-9-12-26(13-10-17)21-6-3-11-24-23(21)29-19-14-27(15-19)22-8-7-18-4-1-2-5-20(18)25-22/h1-8,11,17,19,28H,9-10,12-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assay				Bioorg Med Chem 22: 6570-85 (2015) Article DOI: 10.1016/j.bmc.2014.10.013 BindingDB Entry DOI: 10.7270/Q2RB766Q
					More data for this Ligand-Target Pair