BDBM50037397 6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one::CHEMBL115102

SMILES: Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1

InChI Key: InChIKey=PQNPYVSRVAECJJ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50037397 (6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one...) Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1 Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-2-8(4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.				J Med Chem 37: 3353-62 (1994) BindingDB Entry DOI: 10.7270/Q2D21WNP
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50037397 (6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one...) Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1 Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-2-8(4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATP				J Med Chem 37: 3353-62 (1994) BindingDB Entry DOI: 10.7270/Q2D21WNP
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50037397 (6-Amino-2-(3-amino-phenyl)-7-hydroxy-chromen-4-one...) Show SMILES Nc1cccc(c1)-c1cc(=O)c2cc(N)c(O)cc2o1 Show InChI InChI=1S/C15H12N2O3/c16-9-3-1-2-8(4-9)14-6-12(18)10-5-11(17)13(19)7-15(10)20-14/h1-7,19H,16-17H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATP				J Med Chem 37: 3353-62 (1994) BindingDB Entry DOI: 10.7270/Q2D21WNP
					More data for this Ligand-Target Pair