BDBM50037560 (S)-2-({(R)-1-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-carbamoyl-butyryl]-pyrrolidine-2-carbonyl}-amino)-pentanedioic acid 5-amide 1-{[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide}::CHEMBL325517
SMILES: N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChI Key: InChIKey=CTGJSFUSBYTRFF-NXUCNJKMSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NPFF2 (RAT) | BDBM50037560 ((S)-2-({(R)-1-[(S)-2-((S)-2-Amino-3-phenyl-propion...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Binding affinity for NPPF receptor in rat spinal cord membranes using the radioligand [125I]-[Tyr1]NPFF | J Med Chem 37: 3477-81 (1994) BindingDB Entry DOI: 10.7270/Q20R9NGR | |||||||||||
More data for this Ligand-Target Pair |