BDBM50038870 4-Indan-2-yl-1-[(R)-4-(pyrrolidine-1-carbonyl)-thiazolidin-3-yl]-butan-1-one::CHEMBL416866

SMILES: O=C(CCCC1Cc2ccccc2C1)N1CSC[C@H]1C(=O)N1CCCC1

InChI Key: InChIKey=VZRRVKMHMWPNFF-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038870   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50038870 (4-Indan-2-yl-1-[(R)-4-(pyrrolidine-1-carbonyl)-thi...) Show SMILES O=C(CCCC1Cc2ccccc2C1)N1CSC[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C21H28N2O2S/c24-20(9-5-6-16-12-17-7-1-2-8-18(17)13-16)23-15-26-14-19(23)21(25)22-10-3-4-11-22/h1-2,7-8,16,19H,3-6,9-15H2/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Zeria Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against purified prolyl endopeptidase (PEP) from canine brain.				J Med Chem 37: 2071-8 (1994) BindingDB Entry DOI: 10.7270/Q270822J
					More data for this Ligand-Target Pair