BDBM50038985 3-Benzo[1,3]dioxol-5-ylmethyl-6-methylsulfanyl-3H-quinazolin-4-one::CHEMBL67736

SMILES: CSc1ccc2ncn(Cc3ccc4OCOc4c3)c(=O)c2c1

InChI Key: InChIKey=PPOKXJQYYQBZNT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50038985 (3-Benzo[1,3]dioxol-5-ylmethyl-6-methylsulfanyl-3H-...) Show SMILES CSc1ccc2ncn(Cc3ccc4OCOc4c3)c(=O)c2c1 Show InChI InChI=1S/C17H14N2O3S/c1-23-12-3-4-14-13(7-12)17(20)19(9-18-14)8-11-2-5-15-16(6-11)22-10-21-15/h2-7,9H,8,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against cGMP-phosphodiesterase from porcine aorta				J Med Chem 37: 2106-11 (1994) BindingDB Entry DOI: 10.7270/Q2Q52NPF
					More data for this Ligand-Target Pair