BDBM50039326 CHEMBL3355873

SMILES: COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCn1ccnc1[N+]([O-])=O

InChI Key: InChIKey=HVFMZQWDMHJYLI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50039326 (CHEMBL3355873) Show SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCn1ccnc1[N+]([O-])=O Show InChI InChI=1S/C20H16ClFN6O4/c1-31-17-10-16-13(9-18(17)32-7-6-27-5-4-23-20(27)28(29)30)19(25-11-24-16)26-12-2-3-15(22)14(21)8-12/h2-5,8-11H,6-7H2,1H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Eur J Med Chem 89: 826-34 (2014) Article DOI: 10.1016/j.ejmech.2014.11.010 BindingDB Entry DOI: 10.7270/Q24F1SC5
					More data for this Ligand-Target Pair