BDBM50040450 CHEMBL3352899

SMILES: COc1cc2c(Nc3cccc(Br)c3)ncnc2cc1OCCCCCCn1ccnc1[N+]([O-])=O

InChI Key: InChIKey=WZOUZPGXWHMMHZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50040450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50040450 (CHEMBL3352899) Show SMILES COc1cc2c(Nc3cccc(Br)c3)ncnc2cc1OCCCCCCn1ccnc1[N+]([O-])=O Show InChI InChI=1S/C24H25BrN6O4/c1-34-21-14-19-20(27-16-28-23(19)29-18-8-6-7-17(25)13-18)15-22(21)35-12-5-3-2-4-10-30-11-9-26-24(30)31(32)33/h6-9,11,13-16H,2-5,10,12H2,1H3,(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) by Z'-Lyte kinase assay				Bioorg Med Chem 22: 6796-805 (2015) Article DOI: 10.1016/j.bmc.2014.10.038 BindingDB Entry DOI: 10.7270/Q22J6DHQ
					More data for this Ligand-Target Pair