BDBM50040468 2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethyl)phenoxy]sulfonyl]carbamate,Monosodium salt::Acylphosphoramidate analogue::CHEMBL25110::Sodium salt of 2,6-bis(1-methylethyl)phenyl[[2,6-bis(1-methyl)phenoxy]-sulfonyl]carbamate::Sodium salt of CarboSulfamic acid Bis-(2,6-diisopropyl-phenyl ester)::sodium salt of 2,6-isopropylphenylcraboxy-sulfamic acid 2,6-diisopropyl-phenyl ester::sodium salt of Acyl Sulfamate derivatives

SMILES: CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C

InChI Key: InChIKey=MHCQGCLTFBMETG-UHFFFAOYSA-M

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50040468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50040468 (2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...) Show SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C25H35NO5S/c1-15(2)19-11-9-12-20(16(3)4)23(19)30-25(27)26-32(28,29)31-24-21(17(5)6)13-10-14-22(24)18(7)8/h9-18H,1-8H3,(H,26,27)/p-1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of ACAT by incubation with [1-14C]-oleolyl-CoA and intestinal microsomes isolated from cholesterol-fed rabbits.				Bioorg Med Chem Lett 8: 289-94 (1999) BindingDB Entry DOI: 10.7270/Q2DN446R
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50040468 (2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...) Show SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C25H35NO5S/c1-15(2)19-11-9-12-20(16(3)4)23(19)30-25(27)26-32(28,29)31-24-21(17(5)6)13-10-14-22(24)18(7)8/h9-18H,1-8H3,(H,26,27)/p-1	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rabbit intestinal microsomes				J Med Chem 41: 2390-410 (1998) Article DOI: 10.1021/jm9800853 BindingDB Entry DOI: 10.7270/Q2MW2G7V
					More data for this Ligand-Target Pair
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50040468 (2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...) Show SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C25H35NO5S/c1-15(2)19-11-9-12-20(16(3)4)23(19)30-25(27)26-32(28,29)31-24-21(17(5)6)13-10-14-22(24)18(7)8/h9-18H,1-8H3,(H,26,27)/p-1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferase 1 in microsomes of rat liver				J Med Chem 39: 1243-52 (1996) Article DOI: 10.1021/jm9509455 BindingDB Entry DOI: 10.7270/Q28S4QKV
					More data for this Ligand-Target Pair
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50040468 (2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...) Show SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C25H35NO5S/c1-15(2)19-11-9-12-20(16(3)4)23(19)30-25(27)26-32(28,29)31-24-21(17(5)6)13-10-14-22(24)18(7)8/h9-18H,1-8H3,(H,26,27)/p-1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in liver microsomes of cholesterol fed rats				Bioorg Med Chem Lett 5: 2367-2370 (1995) Article DOI: 10.1016/0960-894X(95)00408-L BindingDB Entry DOI: 10.7270/Q21R6QF9
					More data for this Ligand-Target Pair
Sterol O-acyltransferase, Soat (Rattus norvegicus)	BDBM50040468 (2,6-Bis(1-methylethyl)phenyl[[2,6-Bis(1-methylethy...) Show SMILES CC(C)c1cccc(C(C)C)c1OC(=O)[N-]S(=O)(=O)Oc1c(cccc1C(C)C)C(C)C Show InChI InChI=1S/C25H35NO5S/c1-15(2)19-11-9-12-20(16(3)4)23(19)30-25(27)26-32(28,29)31-24-21(17(5)6)13-10-14-22(24)18(7)8/h9-18H,1-8H3,(H,26,27)/p-1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was evaluated for the Acyl coenzyme A:cholesterol acyltransferase inhibition using microsomes isolated from the livers of cholesterol fed ra...				J Med Chem 37: 560-2 (1994) BindingDB Entry DOI: 10.7270/Q2542MN8
					More data for this Ligand-Target Pair