null

SMILES: CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCn1c(=O)c2cc3c(cc2c1=O)c(=O)[nH]c3=O)C(O)=O

InChI Key: InChIKey=DXBIPBLPCDPKOH-VJBWXMMDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50040585 ((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCn1c(=O)c2cc3c(cc2c1=O)c(=O)[nH]c3=O)C(O)=O Show InChI InChI=1S/C30H33N5O8/c1-15(2)11-22(27(39)33-23(26(38)31-3)12-16-7-5-4-6-8-16)32-21(30(42)43)9-10-35-28(40)19-13-17-18(14-20(19)29(35)41)25(37)34-24(17)36/h4-8,13-15,21-23,32H,9-12H2,1-3H3,(H,31,38)(H,33,39)(H,42,43)(H,34,36,37)/t21-,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human gelatinase (MMP-9).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50040585 ((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCn1c(=O)c2cc3c(cc2c1=O)c(=O)[nH]c3=O)C(O)=O Show InChI InChI=1S/C30H33N5O8/c1-15(2)11-22(27(39)33-23(26(38)31-3)12-16-7-5-4-6-8-16)32-21(30(42)43)9-10-35-28(40)19-13-17-18(14-20(19)29(35)41)25(37)34-24(17)36/h4-8,13-15,21-23,32H,9-12H2,1-3H3,(H,31,38)(H,33,39)(H,42,43)(H,34,36,37)/t21-,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human collagenase (MMP-1).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50040585 ((R)-2-[(S)-3-Methyl-1-((S)-1-methylcarbamoyl-2-phe...) Show SMILES CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)N[C@H](CCn1c(=O)c2cc3c(cc2c1=O)c(=O)[nH]c3=O)C(O)=O Show InChI InChI=1S/C30H33N5O8/c1-15(2)11-22(27(39)33-23(26(38)31-3)12-16-7-5-4-6-8-16)32-21(30(42)43)9-10-35-28(40)19-13-17-18(14-20(19)29(35)41)25(37)34-24(17)36/h4-8,13-15,21-23,32H,9-12H2,1-3H3,(H,31,38)(H,33,39)(H,42,43)(H,34,36,37)/t21-,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Incorporated Research Institute Curated by ChEMBL					Assay Description Activity against human stromelysin (MMP-3).				J Med Chem 37: 674-88 (1994) BindingDB Entry DOI: 10.7270/Q2RV0MRC
					More data for this Ligand-Target Pair