BDBM50040674 1-((S)-1-Isobutyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-[4-(1H-tetrazol-5-yl)-phenyl]-urea::CHEMBL349730

SMILES: CC(C)CN1c2ccccc2C(=N[C@H](NC(=O)Nc2ccc(cc2)-c2nnn[nH]2)C1=O)c1ccccc1

InChI Key: InChIKey=GNIGUBCZEVSNOM-RUZDIDTESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50040674 (1-((S)-1-Isobutyl-2-oxo-5-phenyl-2,3-dihydro-1H-be...) Show SMILES CC(C)CN1c2ccccc2C(=N[C@H](NC(=O)Nc2ccc(cc2)-c2nnn[nH]2)C1=O)c1ccccc1 |c:12| Show InChI InChI=1S/C27H26N8O2/c1-17(2)16-35-22-11-7-6-10-21(22)23(18-8-4-3-5-9-18)29-25(26(35)36)30-27(37)28-20-14-12-19(13-15-20)24-31-33-34-32-24/h3-15,17,25H,16H2,1-2H3,(H2,28,30,37)(H,31,32,33,34)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.142	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description The compound was tested for binding activity against Cholecystokinin type B receptor from rat pancreatic tissue using [125]BH CCK-8 as radioligand				J Med Chem 37: 722-4 (1994) BindingDB Entry DOI: 10.7270/Q2CN72ZM
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50040674 (1-((S)-1-Isobutyl-2-oxo-5-phenyl-2,3-dihydro-1H-be...) Show SMILES CC(C)CN1c2ccccc2C(=N[C@H](NC(=O)Nc2ccc(cc2)-c2nnn[nH]2)C1=O)c1ccccc1 |c:12| Show InChI InChI=1S/C27H26N8O2/c1-17(2)16-35-22-11-7-6-10-21(22)23(18-8-4-3-5-9-18)29-25(26(35)36)30-27(37)28-20-14-12-19(13-15-20)24-31-33-34-32-24/h3-15,17,25H,16H2,1-2H3,(H2,28,30,37)(H,31,32,33,34)/t25-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description The compound was tested for binding activity against Cholecystokinin type A receptor from rat pancreatic tissue using [125]BH CCK-A as radioligand				J Med Chem 37: 722-4 (1994) BindingDB Entry DOI: 10.7270/Q2CN72ZM
					More data for this Ligand-Target Pair