BDBM50041230 2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-propionic acid ethyl ester::CHEMBL279367

SMILES: CCOC(=O)C(Cc1ccc(O[C@H]2CCNC2)cc1)c1cc2cc(ccc2o1)C(N)=N

InChI Key: InChIKey=SUGLHOFWNHYTPY-XJDOXCRVSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50041230 (2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrr...) Show SMILES CCOC(=O)C(Cc1ccc(O[C@H]2CCNC2)cc1)c1cc2cc(ccc2o1)C(N)=N Show InChI InChI=1S/C24H27N3O4/c1-2-29-24(28)20(22-13-17-12-16(23(25)26)5-8-21(17)31-22)11-15-3-6-18(7-4-15)30-19-9-10-27-14-19/h3-8,12-13,19-20,27H,2,9-11,14H2,1H3,(H3,25,26)/t19-,20?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro evaluation for the concentration needed for inhibiting thrombin by 50%				J Med Chem 37: 1200-7 (1994) BindingDB Entry DOI: 10.7270/Q2FF3RF6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50041230 (2-(5-Carbamimidoyl-benzofuran-2-yl)-3-[4-((S)-pyrr...) Show SMILES CCOC(=O)C(Cc1ccc(O[C@H]2CCNC2)cc1)c1cc2cc(ccc2o1)C(N)=N Show InChI InChI=1S/C24H27N3O4/c1-2-29-24(28)20(22-13-17-12-16(23(25)26)5-8-21(17)31-22)11-15-3-6-18(7-4-15)30-19-9-10-27-14-19/h3-8,12-13,19-20,27H,2,9-11,14H2,1H3,(H3,25,26)/t19-,20?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Pharmaceutical Company, Ltd. Curated by ChEMBL					Assay Description In vitro evaluation for the concentration needed for inhibiting factor Xa by 50%				J Med Chem 37: 1200-7 (1994) BindingDB Entry DOI: 10.7270/Q2FF3RF6
					More data for this Ligand-Target Pair