BDBM50041299 1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl)-ethanone::CHEMBL23141
SMILES: CN1C2CCC1C(C(C2)c1ccc(C)cc1)C(C)=O
InChI Key: InChIKey=IYPQGOIPSVXEBK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50041299 (1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 122 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wake Forest University Curated by ChEMBL | Assay Description Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes. | J Med Chem 37: 1262-8 (1994) BindingDB Entry DOI: 10.7270/Q2TH8NBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50041299 (1-(8-Methyl-3-p-tolyl-8-aza-bicyclo[3.2.1]oct-2-yl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wake Forest University Curated by ChEMBL | Assay Description Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes. | J Med Chem 37: 1262-8 (1994) BindingDB Entry DOI: 10.7270/Q2TH8NBM | |||||||||||
More data for this Ligand-Target Pair |