BDBM50041522 CHEMBL3358386

SMILES: O=C(Nc1cccnn1)c1cccc(c1)-c1ccc2ccccc2c1

InChI Key: InChIKey=BAHARDUSWCCFJE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent deacetylase sirtuin 2 (Homo sapiens (Human))	BDBM50041522 (CHEMBL3358386) Show SMILES O=C(Nc1cccnn1)c1cccc(c1)-c1ccc2ccccc2c1 Show InChI InChI=1S/C21H15N3O/c25-21(23-20-9-4-12-22-24-20)19-8-3-7-17(14-19)18-11-10-15-5-1-2-6-16(15)13-18/h1-14H,(H,23,24,25)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
The University of Tokyo Curated by ChEMBL					Assay Description Inhibition of GST-tagged human recombinant SIRT2 (34 to 356 residues) expressed in Escherichia coli BL21 using Fluor de Lys-SIRT as substrate incubat...				Bioorg Med Chem 23: 328-39 (2015) Article DOI: 10.1016/j.bmc.2014.11.027 BindingDB Entry DOI: 10.7270/Q2736SJS
					More data for this Ligand-Target Pair