BDBM50041702 4'-(2-Butyl-4-oxo-4,5-dihydro-imidazo[4,5-c]pyridin-3-ylmethyl)-biphenyl-2-carboxylic acid::CHEMBL288705

SMILES: CCCCc1nc2cc[nH]c(=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=RZINJLAVRWFBLD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1A/Type-1B angiotensin II receptor (RAT)	BDBM50041702 (4'-(2-Butyl-4-oxo-4,5-dihydro-imidazo[4,5-c]pyridi...) Show SMILES CCCCc1nc2cc[nH]c(=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H23N3O3/c1-2-3-8-21-26-20-13-14-25-23(28)22(20)27(21)15-16-9-11-17(12-10-16)18-6-4-5-7-19(18)24(29)30/h4-7,9-14H,2-3,8,15H2,1H3,(H,25,28)(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	5.96E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at AT1 receptor in Rattus norvegicus (rat) adrenal cortex membrane				Citation and Details Article DOI: 10.1007/s00044-012-0040-z BindingDB Entry DOI: 10.7270/Q21R6TD3
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50041702 (4'-(2-Butyl-4-oxo-4,5-dihydro-imidazo[4,5-c]pyridi...) Show SMILES CCCCc1nc2cc[nH]c(=O)c2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C24H23N3O3/c1-2-3-8-21-26-20-13-14-25-23(28)22(20)27(21)15-16-9-11-17(12-10-16)18-6-4-5-7-19(18)24(29)30/h4-7,9-14H,2-3,8,15H2,1H3,(H,25,28)(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Curated by ChEMBL					Assay Description Inhibition of Angiotensin II induced contractions in rabbit aortic rings				J Med Chem 37: 1632-45 (1994) BindingDB Entry DOI: 10.7270/Q2RR1X9M
					More data for this Ligand-Target Pair