BDBM50041965 CHEMBL326217::Methyl-{4-oxo-2-propyl-3-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-quinazolin-6-yl}-carbamic acid isobutyl ester

SMILES: CCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(C)C(=O)OCC(C)C

InChI Key: InChIKey=SOMSKQMSQIYKHK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II AT2 (RAT)	BDBM50041965 (CHEMBL326217 | Methyl-{4-oxo-2-propyl-3-[2'-(2H-te...) Show SMILES CCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(C)C(=O)OCC(C)C Show InChI InChI=1S/C31H33N7O3/c1-5-8-28-32-27-16-15-23(37(4)31(40)41-19-20(2)3)17-26(27)30(39)38(28)18-21-11-13-22(14-12-21)24-9-6-7-10-25(24)29-33-35-36-34-29/h6-7,9-17,20H,5,8,18-19H2,1-4H3,(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against Angiotensin II receptor type 2 from rat mid brain using [125I]-Sar1-Ile8-Ang II without BSA				J Med Chem 36: 3207-10 (1993) BindingDB Entry DOI: 10.7270/Q2QR4W6P
					More data for this Ligand-Target Pair
Angiotensin II type 1a (AT-1a) receptor (RABBIT)	BDBM50041965 (CHEMBL326217 | Methyl-{4-oxo-2-propyl-3-[2'-(2H-te...) Show SMILES CCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)N(C)C(=O)OCC(C)C Show InChI InChI=1S/C31H33N7O3/c1-5-8-28-32-27-16-15-23(37(4)31(40)41-19-20(2)3)17-26(27)30(39)38(28)18-21-11-13-22(14-12-21)24-9-6-7-10-25(24)29-33-35-36-34-29/h6-7,9-17,20H,5,8,18-19H2,1-4H3,(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSA				J Med Chem 36: 3207-10 (1993) BindingDB Entry DOI: 10.7270/Q2QR4W6P
					More data for this Ligand-Target Pair